![]() ![]() We obtained no difference between groups according age, weight, intraoperative fentanyl consumption and duration of surgery. Pain at rest was recorded for each patient using NR scale (0–10) in period of 10 min, 30 min, 2 h, 4 h, 8 h, 12 h and 16 h after the surgery. Both groups received acetaminophen 1 g/8 h IV and metamizole 2.5 g/12 h. ![]() kg⁻¹/6 h as standard hospital analgesia protocol.Second group received after operation tramadol 1 mg First group received bilateral ultrasound guided subcostal transversus abdominis plane block with 20 mL of 0.33% bupivacaine per side before operation and tramadol 1 mg We have randomized 76 patients undergoing laparoscopic cholecystectomy to receive either subcostal transversus abdominis plane block (n = 38) or standard postoperative analgesia (n = 38). Our goal was to investigate influence of subcostal transversus abdominis plane block on postoperative pain scores and opioid consumption. Some studies shown beneficial effects of subcostal transversus abdominis plane block on reducing this pain. In addition TAP block can increase the incidence of postoperative nausea and vomiting.Īfter laparoscopic cholecystectomy, patients have moderate pain in the early postoperative period. TAP block would result in less analgesic consumption, less requirement of analgesic, and less pain at 2 h and slightly at 6 h but at 24 h after laparoscopic surgery in comparison with usual care alone or placebo block. There was a significant difference in postoperative nausea and vomiting (random effects model: OR = 2.04, 95% CI, P = 0.34). Meanwhile, pain sores were significantly different at 2 h (MD = -1.55, 95% CI, P < 0.00001), a borderline difference between the groups seen at 6 hours ( MD = -1.13, 95% CI, P = 0.05), and there was not affect pain at 24 h (MD = -0.33, 95% CI, P = 0.14) with TAP block groups compared with the groups without TAP block. Results were produced with a random effects model with 95% confidence intervals (CI).ġ4 trials with a total of 905 patients were included for the analysis, TAP block resulted in significantly less postoperative analgesic consumption at 24 h (MD = -25.46, 95% CI, P < 0.00001), and less number of patients requiring analgesic postoperatively (OR = 0.16, 95% CI 0.03-0.87, P = 0.03). Mean differences (MD) were formulated for continuous data odds ratios (OR) were calculated for dichotomous data. We searched online databases of MEDLINE, EMBASE, Google scholar and The Cochrane Database of Systematic Review. The increasing use of the transversus abdominis plane (TAP) block, as a form of pain relief after laparoscopic surgery, warrants evaluation of its effectiveness, when compared with other analgesic techniques. ![]()
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